DDT is a pesticide that was used heavily worldwide in the 1950s and 1960s both in agricultural production and for malaria control. Concerns about impacts on wildlife populations—particularly predatory birds—led to the phaseout of DDT in many countries in the 1970s. Use of the pesticide for malaria control has continued in some regions, though most countries now rely on combinations of other control methods.
On May 22, 2001, IPEN Participating Organizations agreed, in conjunction with the Conference of Plenipotentiaries for the Stockholm Convention on Persistent Organic Pollutants (POPs), upon a "Stockholm Declaration." A non-profit, non-governmental organization may join IPEN by endorsing the Stockholm Declaration, as well as IPEN's Dubai Declaration for a Toxics-Free Future and Minamata Declaration on Toxic Metals.