Chemicals are polluting oceans and waterways, not only endangering wildlife and those who rely on seafood for sustenance, but threatening the collapse of many fisheries. In combination with global warming, this is a catastrophe in the making. This report is the first to begin to detail the numerous ways and places in which chemical pollution and climate change is destabilizing this marine infrastructure and the world's fisheries. We still have time to stop the destruction, but as this report indicates, we will need to go beyond thinking only about how to control overfishing or manage pollutants in the fish we consume. Our survival, along with that of all other species, will depend on ensuring the health of the entire ocean, an objective we all must work on together to achieve.