DDT and DDE in the Russian Arctic and reproductive health of Indigenous Peoples.
Adverse reproductive health effects of DDT and its metabolites are well known mostly from experiments in vitro and in vivo. Epidemiological data from humans is limited, and there is little information on the reproductive health effects of DDT and its metabolites. Using an extended database (346 records)-personal birth histories, reproductive anamnesis, newborn's cards and maternal serum DDTs concentrations-it was evaluated whether DDT and its main metabolites (4,4 DDE and 4.4 DDT) were responsible for certain reproductive health effects among Russian Arctic Indigenous women. Menstrual history; adverse outcomes of pregnancies among Indigenous and non-Indigenous puerperal women, fetus pathology, offspring sex ratio, possible associations and dose dependencies of adverse outcomes of pregnancies and offspring pathology with blood concentrations of DDTs were studied.
Report: DDT and DDE in the Russian Arctic and reproductive health of Indigenous Peoples